VACCINE
August 2008
Introduction
Patents
Scan Around the Globe
In Focus
Special Feature
Trials and Testing
Awards & Recognition
Business Trends
Expert Coverage
Knowledge Spreads

Previous Issues


VACCINE : Part 11- 24
From the Desk of Chairman
vaccine

Nanoemulsion vaccines have recently shown promise as effective protection against numerous viral diseases. A novel technique, developed by researchers at the University of Michigan, for vaccinating against infectious diseases, using oil-based emulsion placed in the nose, was able to produce a strong immune response against smallpox and HIV in animal studies. It has prompted interest in nanoemulsion vaccines that induce mucosal immunity in which the immune system stops and kills the invader in mucous membranes before it enters the body system. Further research in the field could lead to the development of effective and safer human nanoemulsion vaccines against smallpox, and vaccines able to induce mucosal immunity, cellular immunity and neutralizing antibody to various isolates of HIV virus.

Nanoemulsions are non-toxic lipid droplets, defined as oil-in-water or water-in-oil emulsions having nano particle size, and usually made from surfactants approved for human consumption. Since these are made from surfactants, nanoemulsions are non-toxic, non-irritant, and hence can be deployed on skin and mucous membranes.

 

The Special Feature in the current issue of WISTA: Vaccines gives a brief on the nanoemulsion technology and covers the potential it has as an effective vehicle for controlled delivery of vaccination and therapcutics against a number of infectious diseases. The feature also gives abstracts of a couple of patents recently granted in this filed.

Other features covered are: Patents for 21st Century Applications; Scan Around the Globe; In Focus; Trials and Testing; Business Trends; Awards; Experts Converge; and Knowledge Spreads.


We welcome comments and suggestions from our readers.

Dr K V Swaminathan

Research & Analysis Team

Mr S R Adige - Principal Advisor
Upasana Verma - Sr. Research Scholar
Ms Lalita Gosal- Sr Res Fellow
Dr Shelley Lahiri - Consultant
Mr S S Kalra - Director